The region, in which clotting takes place, becomes warmer than other parts of the body. This change occurs due to the collection of blood near the clot. As the blood has its own temperature, collection of the fluid in the same area leads to warming up of the region. It usually happens when clotting has not been treated for a long time.

Hypercoagulability is the situation in which the blood runs a higher chance of getting clotted when the vessel gets damaged. For instance, healing occurs faster than usual, clotting faster. This increases the chances of improper clotting in the region, leading to worsening of blood clotting situation.

If the artery or vein in the region of bowels or digestive system is affected by clotting, blood starts to collect and spill in the region. The spilled and excess blood enters the bowel and pharynx regions, leading to its discharge. As the bowel region is affected by oxygen, and nutrients, fluids and salts are lost in the region, pushing the body to the state of diarrhea. In diarrhea, along with forceful ejection of undesirable amounts of nutrients and fluids, blood also comes out, leading to bloody diarrhea. If clotting is not treated, severe blood loss takes place, pain increases manifold and chances of death increase.

Due to clotting, the amount of blood increases in certain areas, especially near the clot, leading to development of redness on the skin near the concerned region. On the other hand, some regions are deprived of oxygen. This leads to discoloration of skin above the region. Redness is seen initially, and, if the clot is not treated, discoloration follows. This usually spreads to other parts of the body in time, spreading in parallel with the degrading cell health of the region.

The effect of improper blood clotting depends on the location of clotting. If a clot occurs in the vessels supplying blood to the brain, the brain is deprived of oxygen, leading to degradation of mental health, dementia, nausea, fainting, vomiting, stroke and death. Clotting of blood vessels leading to the heart is even more fatal as it affects the entire body, leading to system failures, heart attacks, stroke and deaths. So, whenever there is a slight pain in the region of internal injury, it is advisable to reach out to the doctor.

Due to clotting, blood fails to reach certain parts of the body. This leads to malfunctioning and death of cells in the region. The nervous system is also affected when blood fails to provide sufficient oxygen to nerves and brain. This leads to the body part being cut off from the brain, leading to loss of sensation in the body. This aggravates to paralysis if the blood clot is not taken care of in time.

Due to deprivation of oxygen and nutrients due to blood clotting, the cells start to run out of fuel. Moreover, carbon dioxide generated in functioning of the cells cannot be removed, leading to the gas trapping in the cells. Both these factors lead to serious degradation of health of cells and tissues, and subsequently the organs. This further leads to reduction in efficiency of certain systems, which leads to weakness in the body. If clotting is not treated, the weakness can aggravate into nausea, dehydration and fainting. Sometimes, it also leads to death.

Pain is a way of signalling by the brain that something is wrong in the system function. When improper clotting takes place, oxygen supply is reduced in several places. Due to the absence of oxygen, cells in the region start to get irritated and die out, leading to generation of pain. The deprivation of oxygen in the body parts is known as ischemic of the tissue. Intensity of the pain depends upon the severity of oxygen deprivation and the number of cells facing the crisis.

Due to improper clotting, sometimes blood vessels grow larger in size in some areas. As these vessels are located very close to the skin, their swelling is also visible on the skin, leading to swellings. In some cases, due to clotting, blood fails to move beyond the clotted part, leading to its collection near the clot. This leads to expansion of blood vessel in the area, which, in turn, leads to swelling.