Weight loss is the reduction of the total mass of the body. It may be due to a number of reasons like loss of body fat, loss of fluid, loss of adipose tissue or lean mass. When weight loss is due to ALL, it generally includes loss of bone mineral deposits, connective tissues, tendons and some muscles as well. This is because ALL alters the metabolism of the body and food is not properly digested which generally causes a release of triglycerides resulting in catabolism of amino acids. Weight loss can also be due to the hormonal disruptions caused by an ALL induced overactive thyroid.

Paleness is when there is abnormal loss of color from the skin, not due to loss of pigment but due to decreased blood supply. If paleness of skin is accompanied by pale tongue, lips, palms, lining of the eyes and inside of the mouth it requires immediate treatment. Detecting paleness in a dark skinned person can be very difficult, while it is easily observed in light skinned people. Paleness is due to decreased blood supply or decreased red blood cell count. When a patient is suffering from ALL, paleness is a symptom that should not be ignored.

Pyrexia or fever is a common medical condition and is marked by an increase in the body temperature much above the normal range of 98- 100 F. This increase in temperature is generally accompanied by shivering and increased muscle tone. When a person is suffering from pyrexia, there is a feeling of cold in spite of the increase in the body temperature. Pyrexia may not seem fatal, but when it is a symptom of ALL, it can be deadly if not treated in time, since the immunity system of the patient is already damaged.

Dyspnea or shortness of breath is a prime symptom of ALL. It includes breathlessness as if you have just finished running a cross-country. It occurs when the required amount of air is not absorbed by the blood or when the lungs are unable to provide enough oxygen for the body. If dyspnea occurs after some heavy exertion or work it is normal, but if it occurs unexpectedly it becomes pathological. If the patient is not suffering from any disease known to cause it, it can be considered to be due to ALL, and immediate treatment should be undertaken.

Fatigue is a state of mental or physical weakness often marked by tired muscles and inability to continue working at the level of your normal working capacity. Fatigue may have chemical causes, in case of ALL it may be due to vitamin or mineral deficiency. It is different form drowsiness since it does not require sleep. Chronic fatigue is when fatigue is persistent for at least a month and is a symptom of a number of diseases such as ALL. ALL induced chronic fatigue is due to decrease in immunity and lack of proper nutrition which makes the body weak from within, decreasing its capacity and strength.

When patients are suffering from ALL, they become more susceptible to bleeding. One of the earliest signs of bleeding due to ALL is the bleeding of gums while eating or brushing. Bleeding of gums can also be accompanied with nosebleeds (epistaxis) and skin bleeding when it is due to ALL. Bleeding gums are one of the first indicators of a weakening of the immune system and since ALL is known to spread very rapidly in the absence of proper treatment, immediate medical help must be taken.

Anorexia is the decreased feeling of hunger and loss of appetite. Sometimes anorexia may be harmless (if it is for a short duration), but generally it results in the weakening of the body and loss of strength. When a patient is suffering from ALL, it is common to experience a loss of appetite since the digestive system is unable to perform its proper function of digesting the food properly. In case anorexia is observed in a person, it should be taken very seriously and expert medical help must be sought.