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Stress Research

Stress: Research


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1. Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood

Since onset of age related diseases and consequent mortality can be predicted to a significant extent by ascertaining the length of the Leukocyte telomere (LTL), and association of stress biomarkers with LTL suggests a possible underlying mechanism of bringing health outcomes through stress.

Via: pnas.org

2. New directions in reducing stress effects on cancer

The latest findings of a study conducted by Professor Amal Melhem-Bertrandt and Professor Anil K. Sood, at Anderson Cancer Unit, reported in Cancer Prevention Research, strongly suggest that neuro endocrine mediators released in response to stress are connected with development of body cancer. The study can offer significant insight towards identifying key mechanisms and most eligible targets, paving the way for the discovery of new drug entities that could prevent or possibly cure stress borne diseases.

Via: cancerpreventionresearch 

3. Y Aminobutyric Acid inhibits tumor growth in mouse models of non small cell lung cancer

A team led by Professor Sculler, Department of Patho biology, College of Veterinary Medicine, University of Tennessee, recognized the association of social stress in promoting Tumour growth in mouse models. Through his study the observation that psychological distress is one of the major contributors towards higher instances of cancer and related mortality, can be established as a fact through further studies.

Via: cancerpreventionresearch

4. Pituitary adrenal responses to stress in women after sexual and Physical abuse

Recent studies suggest people who have been subjected to some form of physical or sexual abuse in their early years are quite vulnerable to psycho pathological conditions. This may be as a direct consequence of mediation of persistent sensitization of hypothalamic pituitary adrenal axis, in building up a mild state of stress in adulthood. When annihilated the mild state of stress changes into more severe conditions identified as psycho pathogenic disorder. Endocrinal hyperactivity leading to increased Corticotropin Releasing Factor (CRF) and increased cortisol levels, coupled with neuronal hyperactivity of autonomic nervous system in response to persistent stress, has pointed out towards the role of CRF: Receptor Antagonists in the prevention and treatment of psycho pathological conditions linked with early life experiences.

Via: jama.ama-assn.org 

5. Maternal psychological stress is a predictor of low birth weight and intrauterine growth retardation:

Professor P H C Rondó and his team from Department of Nutrition, School of Public Health, University of São Paulo, through their work of longitudinal cohort study, confirmed that maternal stress and psychological distress of pregnant individuals, is associated with fetal weight and gestational age, premature delivery, and intrauterine retardation. It points out towards the need to assess the effectiveness of psychological interventions for ensuring maternal and fetal well being.

Via: nature.com/ejcn/journal 

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