Occurrences of diseases, like autism, presence of anxiety and pressure in life, injuries due to accidents and improper medical dosage are other causes that can lead to schizophrenia.

Close relationships also play an important role in developing vulnerability of schizophrenia in the person. Relationship, which lacks emotional bonding and understanding destitute the person from sharing feelings. This develops progressively to isolation, depression and aloofness, which, later on, develop into schizophrenia.

Urban regions are known notoriously for the lack of long-term, close social circles and de-stressing environment, platform for unhealthy drug-use, existence of people of various ethnic cultures and increased isolation – all the components which are responsible for schizophrenia. These components affect the person genetically and psychologically, leading to schizophrenia.

Environment plays an important factor in the development of schizophrenia. Children born to migrating or frequently travelling parents fail to develop a long-term social circle and lacks time required for developing one, leading to his/her isolation. Those with emotional stresses and anxiety in past and present also face higher chances of schizophrenia. Childhood traumas and events also trigger psychological changes in the person, leading to increase in the risk of contracting schizophrenia.

Consumption of certain substances, such as cannabis, hallucinogens and tobacco, can increase the risk of schizophrenia in the person, though they are not directly related with the disease. The reason for this is not yet known, but it is believed that these substances somehow act in certain portions of brain, leading to the occurrence of the disease.

There are some events in the childhood that sets the path for the occurrence of schizophrenia in later life. People with low IQ levels, shy, poor academic performances and extreme emotional problems happen to affect proper development of the brain. Children known for unpopularity in schools and other people, poorer family-background, immaturity and poor peer engagement cannot develop themselves for larger social circles, leading to their aloofness and inability to interact with others in later part of life. Due to this, schizophrenia becomes nearly inevitable to come in the person.

Mother’s low IQ level and her inability to interact with others also plays an important part, as she is the one the child looks for guidance in his/her initial years.

Infections, especially those affecting the nervous system in a way or other, play a role in development of schizophrenia. Diseases, like influenza, polio, Asian flu and measles, have been found to make children more vulnerable to the disease in the later life. Some viruses; while interacting with the fetus and child increase chances of schizophrenia in the person.

It is in the pregnancy period when the child is most vulnerable to external factors. These factors shape the entire evolutionary path of the child. Schizophrenia is more likely to happen in this period. It is directly related with maternal stress during the pregnancy period; women facing more stress in the pregnancy period are found giving birth to schizophrenia-affected children.

Malnourished women in pregnancy also give birth to children with higher vulnerability to the disease. Apart from this, births in winter and spring (due to greater occurrence of viral infections and lack of Vitamin D), less-than-average body weight at birth and brain hypoxia (low oxygen levels in brain) during pregnancy can trigger the occurrence of schizophrenia.

Continuously evolving psychology of the child plays a major role in the development of schizophrenia. Genetic imprinting – resemblance of a parent in the child’s DNA – is seen closer to maternal genes in the child. These genes in the long run, evolves in the child. If they fail to provide a balance with other genetic patterns and environment, they can push the person towards schizophrenia.

Genetics play an important factor in determining the vulnerability of the person to schizophrenia. It has been found that children of schizophrenia parents have up to 80% chances of having schizophrenia in later part of life. It has also been found that twins from such parents have very low risk – as low as 15% – of having the disease. It has been found that children of schizophrenia parents, even when brought up away from their parents, contract schizophrenia much faster than others.

Deletion or duplication of some parts of DNA sequences also increases chances of schizophrenia in the person.