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Should You Pop A Blister?

Hello everyone! I have one problem to discuss with you all. I have a blister on my right elbow and its hurting me badly. Its about 2cms big and it gets pressed over whenever I am lying down and sleeping. Is this due to some kind of poison like some spider bite? Its there from a week when I use to go for early morning walk in park. I want to know can I pop it and should you pop a blister?

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