I was infected with mononucleosis when I was 14 years old. Now I am 21 years old and recently I am encountering the same symptoms of tiredness, fever, sore throat and loss of appetite. Have I been infected by this disease again? I want people to respond. I dont want anything to happen now. My life was all on track and now this. This mononucleosis condition really stinks. My question is- Can you get mono twice in your life?