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Is Mesna useful for breast cancer patients?

My wife is 38 years old and she has been suffering from breast cancer for the past one year now.She had been administered with ifosfamide some 1 month back. It benefited her for two weeks or so but later it resulted in toxicity. Her doctor is calling on to use Mesna for her. I would like to know from people if she needs to be administered with Mesna for her toxicity? How will the Mesna be useful for her?

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