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How can depression be cured?

My sister is facing some troubles and she is not letting anyone help her. Everyone thinks she is having a nervous breakdown. What are the symptoms of a nervous breakdown? She has stopped talking to anyone in the family. She always wants to be left alone. Please help us, we had a psychologist come over and see her when she least expected it, we did not let her know it was a doctor. She screams in the middle of the night. I am quite terrified of being next to her. She throws things around. How do we find out the cause of the depression?

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