The blood flow to the kidneys may be disrupted by clots in the blood vessels. Diseases and infections can also cause similar problems. Improper blood flow can cause permanent damage to the kidneys.

The kidneys handle the materials that flow in the blood. Medicines taken by people also form a part of the bloodstream. Excessive and prolonged medication can take its toll on the kidneys. This can lead to acute renal failure over a period of time.

Liver regulates the flow and the pressure of the blood directed to the kidneys. The hormones produced by the liver are responsible for this. Diseases or infections that effect the liver and hence the production of hormones can bring about renal failure.

The different tissues in the kidney are dedicated to specific functions in the task of filtering the blood and managing the water and salt levels in it. Injury to the kidney leads to acute renal failure as the normal functioning of processes is hampered.

Kidney stones can obstruct the flow of urine to the ureter. It is through the ureter that waste in the form of urine moves to the bladder. Obstruction of the ureter is a major problem in the normal functioning of the kidneys and the excretory system as a whole.

Before the filtration by tubules, the glomeruli handle the process of blood filtration. Streptococcal bacterial infections damage the glomeruli. The color of urine is dark for a person suffering from this problem. Medication can prove effective but if the problem deteriorates significantly, dialysis is required in order to remove the toxins from the blood.

When blood is filtered by the kidneys, the filtered waste is removed with water in the form of urine. This moves to the bladder through ureters. Cancer of the urinary tract or the bladder hinders the removal of the urine from the body. The occurrence of bladder stones is also categorized as a post renal problem that leads to acute renal failure. Bladder issues pose a problem for the functioning of the entire excretory system.

The function of kidney is to filter the blood to remove waste and toxins. Heart is the organ that forms the core of the circulatory system. When the heart fails to function the flow of blood to the kidneys is not normal. This can have a long term impact in the form of renal failure.

In case of an injury or surgery, as the body loses blood, the blood supply to the kidneys decreases. The relaxing of blood vessels due to infections can also disrupt the normal blood flow to the kidneys. This obstructs the functioning of kidneys. The resumption of normal blood flow is essential to contain long term damage.

The removal of toxins from the body and the process of blood filtration is carried out by the tubules of the kidneys. This condition marks an advanced stage in renal failure. Necrosis implies that the tubules lose their functional characteristics. This kind of damage is also caused due to poisons, dyes, toxins and drugs used in chemotherapy. A decreased blood supply to the kidneys also results in tubular necrosis. This kind of damage is irreversible. Patients require regular dialysis to cope with the condition.

The salt and water balance of the blood is maintained by the interstitial tissue of the kidneys. Inflammation of this tissue occurs in case of people suffering from immunity related diseases such as leukemia and lymphoma. Antibiotics and drugs, such as aspirin and ibuprofen, also have the same impact. Discontinuing the use of such drugs proves beneficial. Treatment with medication is possible. If the damage goes unnoticed for long, acute renal failure is a possibility.